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SBI-477

Product Specifications

CAS Number

781628-99-7

Target

IGF-1R

Applications

Protein Tyrosine Kinase

Molecular Formula

C24H25N3O6S

Additionnal Information

SBI-477 is an insulin signaling inhibitor that deactivates the transcription factor MondoA, leading to reduced expression of the insulin pathway suppressors thioredoxin-interacting protein (TXNIP) and arrestin domain-containing 4 (ARRDC4) . SBI-477 inhibits triacylglyceride (TAG) synthesis and enhances basal glucose uptake in human skeletal myocytes.

Storage Conditions

3 years -20°C powder

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