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Romidepsin (FK228)

Product Specifications

CAS Number

128517-07-7

Synonyms

FK228, Depsipeptide, FR 901228, NSC 630176

Target

HDAC

Applications

DNA Damage/DNA Repair

Smiles

CC=C1C (=O) NC (C (=O) OC2CC (=O) NC (C (=O) NC (CSSCCC=C2) C (=O) N1) C (C) C) C (C) C

Molecular Formula

C24H36N4O6S2

Additionnal Information

Romidepsin (FK228, Depsipeptide, FR 901228, NSC 630176) is a potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM in cell-free assays, respectively. Romidepsin (FK228/depsipeptide) controls growth and induces apoptosis in neuroblastoma tumor cells.

Storage Conditions

2 years -80 in solvent

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