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Rivaroxaban

Product Specifications

CAS Number

366789-02-8

Synonyms

BAY 59-7939

Target

Factor Xa

Applications

Metabolism

Smiles

C1COCC (=O) N1C2=CC=C (C=C2) N3CC (OC3=O) CNC (=O) C4=CC=C (S4) Cl

Molecular Formula

C19H18ClN3O5S

Additionnal Information

Rivaroxaban is a direct inhibitor of Factor Xa with Ki and IC50 of 0.4 nM and 0.7 nM in cell-free assays, respectively. It is selective for human factor Xa, for which it has >10 000-fold greater selectivity than for other biologically relevant serine proteases (IC50 >20 μM) .

Storage Conditions

2 years -80 in solvent

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