4-Methyl-2-oxovaleric acid
Product Specifications
CAS Number
816-66-0
Synonyms
Ketoleucine, 4-MOV, KIC, 4-Methyl-2-oxopentanoic acid, alpha-Ketoisocaproic acid, alpha-ketoisocaproate, 2-Oxoisohexanoate
Target
OXPHOS
Applications
Apoptosis
Smiles
CC (C) CC (=O) C (O) =O
Molecular Formula
C6H10O3
Additionnal Information
4-Methyl-2-oxovaleric acid (Ketoleucine, 4-MOV, KIC, 4-Methyl-2-oxopentanoic acid, alpha-Ketoisocaproic acid, alpha-ketoisocaproate, 2-Oxoisohexanoate) is released by Astrocytes to neurons and can be reaminated by aminotransferase to leucine. 4-Methyl-2-oxovaleric acid reduces the rate of protein degradation in skeletal muscle. 4-Methyl-2-oxovaleric acid acts as an uncoupler of oxidative phosphorylation (OXPHOS) and as a metabolic inhibitor possibly through its inhibitory effect on alpha-ketoglutarate dehydrogenase (oxoglutarate dehydrogenase complex, OGDC) activity.
Storage Conditions
2 years -20°C liquid
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6320823-01 0.2 mL
MIIP, CT (MIIP, IIP45, Migration and invasion-inhibitory protein, IGFBP2-binding protein, Invasion-inhibitory protein 45) (APC)
Sign In for Pricing
View Details MBS6320823-02 5x 0.2 mL
MIIP, CT (MIIP, IIP45, Migration and invasion-inhibitory protein, IGFBP2-binding protein, Invasion-inhibitory protein 45) (APC)
Sign In for Pricing
View Details