SEC inhibitor KL-1
Product Specifications
CAS Number
900308-84-1
Synonyms
KL-1
Target
Others
Applications
Others
Smiles
COC1=CC=CC (=C1) C (=O) CC (=O) C (=O) NC2=C (C) C=CC (=C2) Cl
Molecular Formula
C18H16ClNO4
Additionnal Information
SEC inhibitor KL-1 (KL-1) is a potent and selective inhibitor of super elongation complex (SEC) that disrupts the interaction between the SEC scaffolding protein AFF4 and P-TEFb, resulting in impaired release of Pol II from promoter-proximal pause sites and a reduced average rate of processive transcription elongation. KL-1 exhibits an dose-dependent inhibitory effect on AFF4-CCNT1 interaction with Ki of 3.48 μM.
Storage Conditions
3 years -20°C powder
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
129392-APC 100 µL
MAPK1 (Mitogen-activated Protein Kinase 1, MAPK 1, MAP Kinase 1, ERT1, Extracellular Signal-regulated Kinase 2, ERK2, ERK-2, ERK, MAP Kinase Isoform p42, Mitogen-activated Protein Kinase 2, MAP Kinase 2, MAPK 2, MAPK2, p41mapk, p42-MAPK, P42MAPK, PRKM1, PRKM2) APC discontinued
Sign In for Pricing
View Details 
PGS21A-50 50 Tests
MODIfinder Real-Time PCR MultiSCREEN 3-plex kit for the detection of GM soy CV127+MON87701/DP305423+DP356043/MON87708+MON87769
Sign In for Pricing
View Details 
GTR15185678 1 Vial
Lentiviral mouse Sln shRNA (UAS) - Lentiviral mouse Sln shRNA (UAS, iRFP) (25)
Sign In for Pricing
View Details 
032051-ML650 100 µL
ARHGEF33, CT (ARHGEF33, Rho guanine nucleotide exchange factor 33) (MaxLight 650) discontinued
Sign In for Pricing
View Details