XE991 dihydrochloride
Product Specifications
CAS Number
122955-13-9
Synonyms
LS190926 dihydrochloride
Target
Potassium Channel
Applications
Transmembrane Transporters
Smiles
Cl.Cl.O=C1C2=CC=CC=C2C (CC3=CC=NC=C3) (CC4=CC=NC=C4) C5=CC=CC=C15
Molecular Formula
C26H22Cl2N2O
Additionnal Information
XE 991 (LS190926) dihydrochloride is a blocker of Kv7 (KCNQ) channels that potently inhibits KCNQ1 (Kv7.1), KCNQ2 (Kv7.2), KCNQ2 + KCNQ3 (Kv7.3) channel, and M-current with IC50 of 0.75 μM, 0.71 μM, 0.6 μM, and 0.98 μM, respectively.
Storage Conditions
3 years -20°C powder
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