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Apoptosis Activator 2

Product Specifications

CAS Number

79183-19-0

Target

Caspase

Applications

Apoptosis

Smiles

C1=CC=C2C (=C1) C (=O) C (=O) N2CC3=CC (=C (C=C3) Cl) Cl

Molecular Formula

C15H9Cl2NO2

Additionnal Information

Apoptosis Activator 2 strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation which leads to the destruction of cells (Apaf-1 dependent) with IC50 of ~4 μM, inactive to HMEC, PREC, or MCF-10A cells.

Storage Conditions

2 years -80 in solvent

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