Pirfenidone
Product Specifications
CAS Number
53179-13-8
Synonyms
S-7701, AMR-69
Target
TGF-beta/Smad
Applications
TGF-beta/Smad
Smiles
CC1=CN (C (=O) C=C1) C2=CC=CC=C2
Molecular Formula
C12H11NO
Additionnal Information
Pirfenidone is an inhibitor for TGF-β production and TGF-β stimulated collagen production, reduces production of TNF-α and IL-1β, and also has anti-fibrotic and anti-inflammatory properties. Pirfenidone attenuates chemokine (CC motif) ligand-2 (CCL2) and CCL12 production with anti-fibrotic activity. Phase 3.
Storage Conditions
2 years -80 in solvent
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CDK10 (Cyclin-dependent Kinase 10, PISSLRE, CDC2-related Protein Kinase, Cell Division Protein Kinase 10, Cyclin-dependent Kinase (CDC2-like) 10, Cyclin-dependent Kinase Related Protein, Serine/Threonine Protein Kinase PISSLRE)
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