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Pirfenidone

Product Specifications

CAS Number

53179-13-8

Synonyms

S-7701, AMR-69

Target

TGF-beta/Smad

Applications

TGF-beta/Smad

Smiles

CC1=CN (C (=O) C=C1) C2=CC=CC=C2

Molecular Formula

C12H11NO

Additionnal Information

Pirfenidone is an inhibitor for TGF-β production and TGF-β stimulated collagen production, reduces production of TNF-α and IL-1β, and also has anti-fibrotic and anti-inflammatory properties. Pirfenidone attenuates chemokine (CC motif) ligand-2 (CCL2) and CCL12 production with anti-fibrotic activity. Phase 3.

Storage Conditions

2 years -80 in solvent

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