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VU 0361737

Product Specifications

CAS Number

1161205-04-4

Target

GluR

Applications

Neuronal Signaling

Smiles

COC1=C (C=CC (=C1) NC (=O) C2=CC=CC=N2) Cl

Molecular Formula

C13H11ClN2O2

Additionnal Information

VU 0361737 is a selective positive allosteric modulator (PAM) for mGlu4 receptor with EC50 of 240 nM and 110 nM at human and rat receptors, respectively, displays weak activity at mGlu5 and mGlu8 receptors, is inactive at mGlu1, mGlu2, mGlu3, mGlu6 and mGlu7 receptors, can penetrate into CNS.

Storage Conditions

2 years -80 in solvent

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