GW441756
Product Specifications
CAS Number
504433-23-2
Target
Trk receptor
Applications
Protein Tyrosine Kinase
Smiles
CN1C=C (C2=CC=CC=C21) C=C3C4=C (C=CC=N4) NC3=O
Molecular Formula
C17H13N3O
Additionnal Information
GW441756 is a potent, selective inhibitor of TrkA with IC50 of 2 nM, with very little activity to c-Raf1 and CDK2. GW441756 produces a relevant increase of caspase-3 that leads to apoptosis.
Storage Conditions
2 years -80 in solvent
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