PF-562271
Product Specifications
CAS Number
717907-75-0
Synonyms
PF-00562271
Target
FAK
Applications
Protein Tyrosine Kinase
Smiles
CN (C1=C (C=CC=N1) CNC2=NC (=NC=C2C (F) (F) F) NC3=CC4=C (C=C3) NC (=O) C4) S (=O) (=O) C
Molecular Formula
C21H20F3N7O3S
Additionnal Information
PF-562271 (PF-00562271) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.
Storage Conditions
2 years -80 in solvent
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