What is the catalog number for IKK-16?

The catalog number for IKK-16 is C08935-10mM/1mL.

What sizes are available for IKK-16?

IKK-16 is available in the following size(s): 10 mM/1mL.

IKK-16 is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for IKK-16?

IKK-16 is requires dry ice shipping.

IKK-16

Product Specifications

CAS Number

873225-46-8

Synonyms

IKK Inhibitor VII

Target

IκB/IKK

Applications

NF-κB

Smiles

C1CCN (C1) C2CCN (CC2) C (=O) C3=CC=C (C=C3) NC4=NC=CC (=N4) C5=CC6=CC=CC=C6S5

Molecular Formula

C28H29N5OS

Additionnal Information

IKK-16 is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM in cell-free assays, respectively. IKK-16 also inhibits LRRK2 Ser935 phosphorylation in cells and LRRK2 kinase activity in vitro with IC50 of 50 nM.