T0070907
Product Specifications
CAS Number
313516-66-4
Target
PPAR
Applications
DNA Damage/DNA Repair
Smiles
C1=CC (=C (C=C1[N+] (=O) [O-]) C (=O) NC2=CC=NC=C2) Cl
Molecular Formula
C12H8ClN3O3
Additionnal Information
T0070907 is a potent inhibitor of PPARγ (peroxisome proliferator activator receptor γ) that induces G2/M arrest and enhances the effect of radiation in human cervical cancer cells through mitotic catastrophe. It also acts as an antagonist of PPARγ that suppresses breast cancer cell proliferation and motility via both PPARgamma-dependent and -independent mechanisms.
Storage Conditions
2 years -80 in solvent
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