Golvatinib (E7050)
Product Specifications
CAS Number
928037-13-2
Target
C-Met
Applications
Protein Tyrosine Kinase
Smiles
CN1CCN (CC1) C2CCN (CC2) C (=O) NC3=NC=CC (=C3) OC4=CC (=C (C=C4) NC (=O) C5 (CC5) C (=O) NC6=CC=C (C=C6) F) F
Molecular Formula
C33H37F2N7O4
Additionnal Information
Golvatinib (E7050) is a dual c-Met and VEGFR-2 inhibitor with IC50 of 14 nM and 16 nM, does not inhibit bFGF-stimulated HUVEC growth (up to 1000 nM) . Phase 1/2.
Storage Conditions
2 years -80 in solvent
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USP6 (Deubiquitinating enzyme 6, HRP1, Hyperpolymorphic gene 1, Proto-oncogene TRE-2, TRE17, TRE2, Tre-2, Tre-2 oncogene, Ubiquitin carboxyl-terminal hydrolase 6, Ubiquitin specific peptidase 6, Ubiquitin specific peptidase 6 (Tre-2 oncogene), Ubiquitin specific protease 6 (Tre-2 oncogene), Ubiquitin thioesterase 6, Ubiquitin thiolesterase 6, Ubiquitin-specific protease, Ubiquitin-specific-processing protease 6, USP6, USP6-short)
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