Semaxanib (SU5416)
Product Specifications
CAS Number
204005-46-9
Synonyms
Semaxinib
Target
VEGFR
Applications
Protein Tyrosine Kinase
Smiles
CC1=CC (=C (N1) C=C2C3=CC=CC=C3NC2=O) C
Molecular Formula
C15H14N2O
Additionnal Information
Semaxanib (SU5416, semaxinib) is a potent and selective VEGFR (Flk-1/KDR) inhibitor with IC50 of 1.23 μM, 20-fold more selective for VEGFR than PDGFRβ, lack of activity against EGFR, InsR and FGFR. Phase 3.Semaxanib (SU5416) can be used to induce animal models of chronic intermittent hypoxia.
Storage Conditions
2 years -80 in solvent
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