BI-D1870
Product Specifications
CAS Number
501437-28-1
Target
S6 Kinase
Applications
MAPK
Smiles
CC1C (=O) N (C2=CN=C (N=C2N1CCC (C) C) NC3=CC (=C (C (=C3) F) O) F) C
Molecular Formula
C19H23F2N5O2
Additionnal Information
BI-D1870 is an ATP-competitive inhibitor of S6 ribosome for RSK1/2/3/4 with IC50 of 31 nM/24 nM/18 nM/15 nM in cell-free assays, respectively; 10- to 100-fold selectivity for RSK than MST2, GSK-3β, MARK3, CK1 and Aurora B. BI-D1870 exhibits anticancer attributes including the generation of reactive oxygen species (ROS) and increases in endoplasmic reticulum (ER) stress and autophagy.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS7023303-01 0.02 mg
Recombinant Mouse Putative small membrane protein NID67 (Nid67)
Sign In for Pricing
View Details MBS7023303-02 0.1 mg
Recombinant Mouse Putative small membrane protein NID67 (Nid67)
Sign In for Pricing
View Details MBS7023303-03 5x 0.1 mg
Recombinant Mouse Putative small membrane protein NID67 (Nid67)
Sign In for Pricing
View Details 
H00006133-P01-25ug 25 µg
Recombinant Human RPL9 Protein - (Dry Ice)
Sign In for Pricing
View Details PC103012-01 100 mg
6-Bromo-5-chloro-7-fluorobenzo[c]isothiazol-3-amine
Sign In for Pricing
View Details