TPCA-1
Product Specifications
CAS Number
507475-17-4
Synonyms
GW683965
Target
IκB/IKK
Applications
NF-κB
Smiles
C1=CC (=CC=C1C2=CC (=C (S2) NC (=O) N) C (=O) N) F
Molecular Formula
C12H10FN3O2S
Additionnal Information
TPCA-1 (GW683965) is an inhibitor of IKK-2 with IC50 of 17.9 nM in a cell-free assay, inhibits NF-κB pathway, exhibits 22-fold selectivity over IKK-1. TPCA-1 is also an inhibitor of STAT3 and enhances apoptosis.
Storage Conditions
2 years -80 in solvent
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