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TAE226 (NVP-TAE226)

Product Specifications

CAS Number

761437-28-9

Target

FAK

Applications

Protein Tyrosine Kinase

Smiles

CNC (=O) C1=CC=CC=C1NC2=NC (=NC=C2Cl) NC3=C (C=C (C=C3) N4CCOCC4) OC

Molecular Formula

C23H25ClN6O3

Additionnal Information

TAE226 (NVP-TAE226) is a potent FAK inhibitor with IC50 of 5.5 nM and modestly potent to Pyk2, ~10- to 100-fold less potent against InsR, IGF-1R, ALK, and c-Met. TAE226 (NVP-TAE226) induces apoptosis.

Storage Conditions

2 years -80 in solvent

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