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LY364947

Product Specifications

CAS Number

396129-53-6

Synonyms

HTS 466284

Target

TGF-beta/Smad

Applications

TGF-beta/Smad

Smiles

C1=CC=C2C (=C1) C (=CC=N2) C3=C (NN=C3) C4=CC=CC=N4

Molecular Formula

C17H12N4

Additionnal Information

LY364947 (HTS 466284) is a potent ATP-competitive inhibitor of TGFβR-I with IC50 of 59 nM in a cell-free assay, shows 7-fold selectivity over TGFβR-II.

Storage Conditions

2 years -80 in solvent

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