What is the catalog number for Tofacitinib (CP-690550)?

The catalog number for Tofacitinib (CP-690550) is C17069-10mM/1mL.

What sizes are available for Tofacitinib (CP-690550)?

Tofacitinib (CP-690550) is available in the following size(s): 10 mM/1mL.

Is Tofacitinib (CP-690550) in stock?

Tofacitinib (CP-690550) is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for Tofacitinib (CP-690550)?

Tofacitinib (CP-690550) is requires dry ice shipping.

Tofacitinib (CP-690550)

Product Specifications

CAS Number

477600-75-2

Synonyms

CP-690550, Tasocitinib

Target

JAK

Applications

Angiogenesis

Smiles

CC1CCN (CC1N (C) C2=NC=NC3=C2C=CN3) C (=O) CC#N

Molecular Formula

C16H20N6O

Additionnal Information

Tofacitinib is a novel inhibitor of JAK3 with IC50 of 1 nM in cell-free assays, 20- to 100-fold less potent against JAK2 and JAK1. Tofacitinib inhibits the expression of antiapoptotic BCL-A1 and BCL-XL in human plasmacytoid dendritic cells (PDC) and induced PDC apoptosis.