What is the catalog number for Tofacitinib?

The catalog number for Tofacitinib is C08859-100mg.

What sizes are available for Tofacitinib?

Tofacitinib is available in the following size(s): 100 mg.

Is Tofacitinib in stock?

Tofacitinib is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for Tofacitinib?

Tofacitinib is requires dry ice shipping.

Tofacitinib

Product Specifications

CAS Number

477600-75-2

Synonyms

CP-690550, Tasocitinib

Target

JAK

Applications

Angiogenesis

Smiles

CC1CCN (CC1N (C) C2=NC=NC3=C2C=CN3) C (=O) CC#N

Molecular Formula

C16H20N6O

Additionnal Information

Tofacitinib is a novel inhibitor of JAK3 with IC50 of 1 nM in cell-free assays, 20- to 100-fold less potent against JAK2 and JAK1. Tofacitinib inhibits the expression of antiapoptotic BCL-A1 and BCL-XL in human plasmacytoid dendritic cells (PDC) and induced PDC apoptosis.