TAK-285
Product Specifications
CAS Number
871026-44-7
Target
EGFR
Applications
Protein Tyrosine Kinase
Smiles
CC (C) (CC (=O) NCCN1C=CC2=C1C (=NC=N2) NC3=CC (=C (C=C3) OC4=CC=CC (=C4) C (F) (F) F) Cl) O
Molecular Formula
C26H25ClF3N5O3
Additionnal Information
TAK-285 is a novel dual HER2 and EGFR (HER1) inhibitor with IC50 of 17 nM and 23 nM, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. Phase 1.
Storage Conditions
2 years -80 in solvent
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