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GW4064

Product Specifications

CAS Number

278779-30-9

Target

FXR

Applications

Metabolism

Smiles

CC (C) C1=C (C (=NO1) C2=C (C=CC=C2Cl) Cl) COC3=CC (=C (C=C3) C=CC4=CC (=CC=C4) C (=O) O) Cl

Molecular Formula

C28H22Cl3NO4

Additionnal Information

GW4064 is an agonist of farnesoid X receptor (FXR) with EC50 of 65 nM in CV1 cell line and displays no activity at other nuclear receptors at concentrations up to 1 μM. GW4064 stimulates autophagy in MCF-7 cells.

Storage Conditions

2 years -80 in solvent

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