GW4064
Product Specifications
CAS Number
278779-30-9
Target
FXR
Applications
Metabolism
Smiles
CC (C) C1=C (C (=NO1) C2=C (C=CC=C2Cl) Cl) COC3=CC (=C (C=C3) C=CC4=CC (=CC=C4) C (=O) O) Cl
Molecular Formula
C28H22Cl3NO4
Additionnal Information
GW4064 is an agonist of farnesoid X receptor (FXR) with EC50 of 65 nM in CV1 cell line and displays no activity at other nuclear receptors at concentrations up to 1 μM. GW4064 stimulates autophagy in MCF-7 cells.
Storage Conditions
2 years -80 in solvent
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