Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

PF-5274857

Product Specifications

CAS Number

1373615-35-0

Target

Hedgehog/Smoothened

Applications

Stem Cells & Wnt

Smiles

CC1=CC (=C (N=C1) C2=CC (=NC=C2Cl) N3CCN (CC3) C (=O) CCS (=O) (=O) C) C

Molecular Formula

C20H25ClN4O3S

Additionnal Information

PF-5274857 is a potent and selective Smoothened (Smo) antagonist, inhibits Hedgehog (Hh) signaling with IC50 and Ki of 5.8 nM and 4.6 nM, respectively, and can penetrate the blood–brain barrier.

Storage Conditions

2 years -80 in solvent

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Lentiviral mouse Pax5 shRNA (UAS) - Lentiviral mouse Pax5 shRNA (UAS, iRFP) plasmid
GTR15281272 1 Vial

Lentiviral mouse Pax5 shRNA (UAS) - Lentiviral mouse Pax5 shRNA (UAS, iRFP) plasmid

Sign In for Pricing
View Details
ING4 Protein Vector (Mouse) (pPB-N-His)
PV191783 500 ng

ING4 Protein Vector (Mouse) (pPB-N-His)

Sign In for Pricing
View Details
STAT3 Antibody
MBS9504275-01 0.05 mL

STAT3 Antibody

Sign In for Pricing
View Details
STAT3 Antibody
MBS9504275-02 0.1 mL

STAT3 Antibody

Sign In for Pricing
View Details
STAT3 Antibody
MBS9504275-03 5x 0.1 mL

STAT3 Antibody

Sign In for Pricing
View Details
Mouse Galectin 2 ELISA Kit
MBS727016-01 48 Strip Well (Competitive)

Mouse Galectin 2 ELISA Kit

Sign In for Pricing
View Details