SB705498
Product Specifications
CAS Number
501951-42-4
Target
TRP Channel
Applications
Neuronal Signaling
Smiles
C1CN (CC1NC (=O) NC2=CC=CC=C2Br) C3=NC=C (C=C3) C (F) (F) F
Molecular Formula
C17H16BrF3N4O
Additionnal Information
SB705498 is a TRPV1 antagonist for hTRPV1, antagonizes capsaicin, acid, and heat activation of TRPV1 with IC50 of 3 nM, 0.1 nM and 6 nM, shows a degree of voltage dependence, exhibits >100-fold selectivity for TRPV1 over TRPM8. Phase 2.
Storage Conditions
2 years -80 in solvent
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