MK-5108
Product Specifications
CAS Number
1010085-13-8
Synonyms
VX-689
Target
Aurora Kinase
Applications
Cell Cycle
Smiles
C1CC (CCC1OC2=C (C (=CC=C2) Cl) F) (CC3=NC (=CC=C3) NC4=NC=CS4) C (=O) O
Molecular Formula
C22H21ClFN3O3S
Additionnal Information
MK-5108 is a highly selective Aurora A inhibitor with IC50 of 0.064 nM in a cell-free assay and is 220- and 190-fold more selective for Aurora A than Aurora B/C, while it inhibits TrkA with less than 100-fold selectivity. MK-5108 (VX-689) induces autophagy. Phase 1.
Storage Conditions
2 years -80 in solvent
More Discoveries
Explore Other Products
Browse additional items from our catalog
28017126 3x 1.0µg DNA
MAP2K4 CRISPRa sgRNA lentivector (set of three targets)(Rat)
Sign In for Pricing
View Details MBS7189558 Inquire
Rabbit anti-Caenorhabditis elegans R10H1.1 Polyclonal Antibody
Sign In for Pricing
View Details 
