Dinaciclib
Product Specifications
CAS Number
779353-01-4
Synonyms
SCH727965, PS-095760
Target
CDK
Applications
Cell Cycle
Smiles
CCC1=C2N=C (C=C (N2N=C1) NCC3=C[N+] (=CC=C3) [O-]) N4CCCCC4CCO
Molecular Formula
C21H28N6O2
Additionnal Information
Dinaciclib is a novel and potent CDK inhibitor for CDK2, CDK5, CDK1 and CDK9 with IC50 of 1 nM, 1 nM, 3 nM and 4 nM in cell-free assays, respectively. It also blocks thymidine (dThd) DNA incorporation. Dinaciclib induces apoptosis through the activation of caspases 8 and 9. Phase 3.
Storage Conditions
2 years -80 in solvent
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