Dinaciclib
Product Specifications
CAS Number
779353-01-4
Synonyms
SCH727965, PS-095760
Target
CDK
Applications
Cell Cycle
Smiles
CCC1=C2N=C (C=C (N2N=C1) NCC3=C[N+] (=CC=C3) [O-]) N4CCCCC4CCO
Molecular Formula
C21H28N6O2
Additionnal Information
Dinaciclib is a novel and potent CDK inhibitor for CDK2, CDK5, CDK1 and CDK9 with IC50 of 1 nM, 1 nM, 3 nM and 4 nM in cell-free assays, respectively. It also blocks thymidine (dThd) DNA incorporation. Dinaciclib induces apoptosis through the activation of caspases 8 and 9. Phase 3.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC470726-500 1x 500 µL
DOG-1 (DG1/447 + DOG1.1), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNCB1884-500 1x 500 µL
Thymidylate Synthase (5-FU Resistance Marker) (TYMS/1884), Biotin conjugate, 0.1mg/mL
Sign In for Pricing
View Details