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Alectinib

Product Specifications

CAS Number

1256580-46-7

Synonyms

AF-802, RG-7853, CH5424802

Target

ALK

Applications

Protein Tyrosine Kinase

Smiles

CCC1=CC2=C (C=C1N3CCC (CC3) N4CCOCC4) C (C5=C (C2=O) C6=C (N5) C=C (C=C6) C#N) (C) C

Molecular Formula

C30H34N4O2

Additionnal Information

Alectinib is a potent ALK inhibitor with IC50 of 1.9 nM in cell-free assays, sensitive to L1196M mutation and higher selectivity for ALK than PF-02341066, NVP-TAE684 and PHA-E429.

Storage Conditions

2 years -80 in solvent

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