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Fimepinostat (CUDC-907)

Product Specifications

CAS Number

1339928-25-4

Target

HDAC

Applications

DNA Damage/DNA Repair

Smiles

CN (CC1=CC2=C (S1) C (=NC (=N2) C3=CN=C (C=C3) OC) N4CCOCC4) C5=NC=C (C=N5) C (=O) NO

Molecular Formula

C23H24N8O4S

Additionnal Information

CUDC-907 is a dual PI3K and HDAC inhibitor for PI3Kα and HDAC1/2/3/10 with IC50 of 19 nM and 1.7 nM/5 nM/1.8 nM/2.8 nM, respectively. CUDC-907 induces cell cycle arrest and apoptosis in breast cancer cells. Phase 1.

Storage Conditions

2 years -80 in solvent

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