Evofosfamide (TH-302)
Product Specifications
CAS Number
918633-87-1
Target
Others
Applications
Others
Smiles
CN1C (=CN=C1[N+] (=O) [O-]) COP (=O) (NCCBr) NCCBr
Molecular Formula
C9H16Br2N5O4P
Additionnal Information
Evofosfamide (TH-302) is a selective hypoxia-activated prodrug targeting hypoxic regions of solid tumors with IC50 of 19 nM, demonstrates 270-fold enhanced cytotoxicity under hypoxia versus their potency under aerobic conditions, stable to cytochrome P450 metabolism.
Storage Conditions
2 years -80 in solvent
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