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Varlitinib

Product Specifications

CAS Number

845272-21-1

Synonyms

ARRY334543

Target

EGFR

Applications

Protein Tyrosine Kinase

Smiles

CC1COC (=N1) NC2=CC3=C (C=C2) N=CN=C3NC4=CC (=C (C=C4) OCC5=NC=CS5) Cl

Molecular Formula

C22H19ClN6O2S

Additionnal Information

Varlitinib (ARRY334543) is a selective and potent ErbB1 (EGFR) and ErbB2 (HER2) inhibitor with IC50 of 7 nM and 2 nM, respectively. Phase 2.

Storage Conditions

2 years -80 in solvent

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