What is the catalog number for Xevinapant (AT406)?

The catalog number for Xevinapant (AT406) is C08831-25mg.

What sizes are available for Xevinapant (AT406)?

Xevinapant (AT406) is available in the following size(s): 25 mg.

Is Xevinapant (AT406) in stock?

Xevinapant (AT406) is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for Xevinapant (AT406)?

Xevinapant (AT406) is requires dry ice shipping.

Xevinapant (AT406)

Product Specifications

CAS Number

1071992-99-8

Synonyms

ARRY-334543, Debio1143, SM-406

Target

E3 Ligase

Applications

Ubiquitin

Smiles

CC (C) CC (=O) N1CCC2CCC (N2C (=O) C (C1) NC (=O) C (C) NC) C (=O) NC (C3=CC=CC=C3) C4=CC=CC=C4

Molecular Formula

C32H43N5O4

Additionnal Information

Xevinapant (AT406, ARRY-334543, Debio1143, SM-406) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide. Phase 1.