Milciclib
Product Specifications
CAS Number
802539-81-7
Synonyms
PHA-848125
Target
CDK
Applications
Cell Cycle
Smiles
CC1 (CC2=CN=C (N=C2C3=C1C (=NN3C) C (=O) NC) NC4=CC=C (C=C4) N5CCN (CC5) C) C
Molecular Formula
C25H32N8O
Additionnal Information
Milciclib is a potent, ATP-competitive CDK inhibitor for CDK2 with IC50 of 45 nM. It is >3-fold more selective for CDK2 than CDK1, 2, 4, 5, and 7, it's also an inhibitor of TRKA with IC50 of 53nM. Milciclib (PHA-848125) induces cell death through autophagy. Phase 2.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6405508-01 0.1 mL
ADAP1 (Arf-GAP with Dual PH Domain-containing Protein 1, GCS1L, CENTA1, p42IP4) (AP)
Sign In for Pricing
View Details MBS6405508-02 5x 0.1 mL
ADAP1 (Arf-GAP with Dual PH Domain-containing Protein 1, GCS1L, CENTA1, p42IP4) (AP)
Sign In for Pricing
View Details 
M4701-95P 200 µg
Mucin 16 (MUC16, MUC-16, CA125, CA-125, Cancer Antigen 125, FLJ14303, Mucin 16 Cell Surface Associated, Cancer-related Tumor Marker CA125, Ovarian Carcinoma Antigen CA125)
Sign In for Pricing
View Details ARO-P18886-01 50 µg
Salmonella enteritidis FliC Recombinant Protein, N-Strep
Sign In for Pricing
View Details ARO-P18886-02 100 µg
Salmonella enteritidis FliC Recombinant Protein, N-Strep
Sign In for Pricing
View Details