GW788388
Product Specifications
CAS Number
452342-67-5
Target
TGF-beta/Smad
Applications
TGF-beta/Smad
Smiles
C1COCCC1NC (=O) C2=CC=C (C=C2) C3=NC=CC (=C3) C4=C (NN=C4) C5=CC=CC=N5
Molecular Formula
C25H23N5O2
Additionnal Information
GW788388 is a potent and selective inhibitor of ALK5 with IC50 of 18 nM in a cell-free assay, also inhibits TGF-β type II receptor and activin type II receptor activities, but does not inhibit BMP type II receptor.
Storage Conditions
2 years -80 in solvent
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