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Anacetrapib (MK-0859)

Product Specifications

CAS Number

875446-37-0

Target

CETP

Applications

Metabolism

Smiles

CC1C (OC (=O) N1CC2=C (C=CC (=C2) C (F) (F) F) C3=CC (=C (C=C3OC) F) C (C) C) C4=CC (=CC (=C4) C (F) (F) F) C (F) (F) F

Molecular Formula

C30H25F10NO3

Additionnal Information

Anacetrapib (MK0859) is a potent, selective, reversible rhCETP and mutant CETP (C13S) inhibitor with IC50 of 7.9 nM and 11.8 nM, increases HDL-C and decreases LDL-C, does not increase aldosterone or blood pressure. Phase 3.

Storage Conditions

2 years -80 in solvent

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