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CHIR-98014

Product Specifications

CAS Number

252935-94-7

Synonyms

CT98014

Target

GSK-3

Applications

PI3K/Akt/mTOR

Smiles

C1=CC (=C (C=C1Cl) Cl) C2=NC (=NC=C2N3C=CN=C3) NCCNC4=NC (=C (C=C4) [N+] (=O) [O-]) N

Molecular Formula

C20H17Cl2N9O2

Additionnal Information

CHIR-98014 (CT98014) is a potent GSK-3α/β inhibitor with IC50 of 0.65 nM/0.58 nM in cell-free assays, with the ability to distinguish GSK-3 from its closest homologs Cdc2 and ERK2.

Storage Conditions

2 years -80 in solvent

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