PF-04691502
Product Specifications
CAS Number
1013101-36-4
Synonyms
PF4691502
Target
Akt
Applications
PI3K/Akt/mTOR
Smiles
CC1=C2C=C (C (=O) N (C2=NC (=N1) N) C3CCC (CC3) OCCO) C4=CN=C (C=C4) OC
Molecular Formula
C22H27N5O4
Additionnal Information
PF-04691502 (PF4691502) is an ATP-competitive PI3K (α/β/δ/γ) /mTOR dual inhibitor with Ki of 1.8 nM/2.1 nM/1.6 nM/1.9 nM and 16 nM in cell-free assays, little activity against either Vps34, AKT, PDK1, p70S6K, MEK, ERK, p38, or JNK. PF-04691502 induces apoptosis. Phase 2.
Storage Conditions
2 years -80 in solvent
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