What is the catalog number for PHA-767491 HCl?

The catalog number for PHA-767491 HCl is C08819-10mM/1mL.

What sizes are available for PHA-767491 HCl?

PHA-767491 HCl is available in the following size(s): 10 mM/1mL.

Is PHA-767491 HCl in stock?

PHA-767491 HCl is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for PHA-767491 HCl?

PHA-767491 HCl is requires dry ice shipping.

PHA-767491 HCl

Product Specifications

CAS Number

942425-68-5

Synonyms

CAY10572, NMS 1116354

Target

CDK

Applications

Cell Cycle

Smiles

C1CNC (=O) C2=C1NC (=C2) C3=CC=NC=C3.Cl

Molecular Formula

C12H11N3O.HCl

Additionnal Information

PHA-767491 (CAY10572, NMS 1116354) HCl is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 nM in cell-free assays, respectively.It displays ~20-fold selectivity against CDK1/2 and GSK3-β, 50-fold selectivity against MK2 and CDK5, 100-fold selectivity against PLK1 and CHK2.