GSK1070916
Product Specifications
CAS Number
942918-07-2
Target
Aurora Kinase
Applications
Cell Cycle
Smiles
CCN1C=C (C (=N1) C2=CC=C (C=C2) NC (=O) N (C) C) C3=C4C=C (NC4=NC=C3) C5=CC=CC (=C5) CN (C) C
Molecular Formula
C30H33N7O
Additionnal Information
GSK1070916 is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM. It displays >100-fold selectivity against the closely related Aurora A-TPX2 complex. Phase 1.
Storage Conditions
2 years -80 in solvent
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