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GSK1070916

Product Specifications

CAS Number

942918-07-2

Target

Aurora Kinase

Applications

Cell Cycle

Smiles

CCN1C=C (C (=N1) C2=CC=C (C=C2) NC (=O) N (C) C) C3=C4C=C (NC4=NC=C3) C5=CC=CC (=C5) CN (C) C

Molecular Formula

C30H33N7O

Additionnal Information

GSK1070916 is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM. It displays >100-fold selectivity against the closely related Aurora A-TPX2 complex. Phase 1.

Storage Conditions

2 years -80 in solvent

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