PH-797804
Product Specifications
CAS Number
586379-66-0
Target
P38 MAPK
Applications
MAPK
Smiles
CC1=C (C=C (C=C1) C (=O) NC) N2C (=CC (=C (C2=O) Br) OCC3=C (C=C (C=C3) F) F) C
Molecular Formula
C22H19BrF2N2O3
Additionnal Information
PH-797804 is a novel pyridinone inhibitor of p38α with IC50 of 26 nM in a cell-free assay; 4-fold more selective versus p38β and does not inhibit JNK2. Phase 2.
Storage Conditions
2 years -80 in solvent
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