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Geldanamycin

Product Specifications

CAS Number

30562-34-6

Synonyms

NSC 122750

Target

HSP (HSP90)

Applications

Cytoskeletal Signaling

Smiles

CC1CC (C (C (C=C (C (C (C=CC=C (C (=O) NC2=CC (=O) C (=C (C1) C2=O) OC) C) OC) OC (=O) N) C) C) O) OC

Molecular Formula

C29H40N2O9

Additionnal Information

Geldanamycin is a natural existing HSP90 inhibitor with Kd of 1.2 μM, specifically disrupts glucocorticoid receptor (GR) /HSP association. Geldanamycin attenuates virus infection-induced ALI (acute lung injury) /ARDS (acute respiratory distress syndrome) by reducing the host's inflammatory responses.

Storage Conditions

2 years -80 in solvent

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