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GSK1838705A

Product Specifications

CAS Number

1116235-97-2

Target

ALK

Applications

Protein Tyrosine Kinase

Smiles

CNC (=O) C1=C (C=CC=C1F) NC2=NC (=NC3=C2C=CN3) NC4=C (C=C5CCN (C5=C4) C (=O) CN (C) C) OC

Molecular Formula

C27H29FN8O3

Additionnal Information

GSK1838705A is a potent IGF-1R inhibitor with IC50 of 2.0 nM, modestly potent to IR and ALK with IC50 of 1.6 nM and 0.5 nM, respectively, and little activity to other protein kinases.

Storage Conditions

2 years -80 in solvent

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