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Nepicastat (SYN-117) HCl

Product Specifications

CAS Number

170151-24-3

Target

Hydroxylase

Applications

Metabolism

Smiles

C1CC2=C (CC1N3C (=CNC3=S) CN) C=C (C=C2F) F.Cl

Molecular Formula

C14H15F2N3S.HCl

Additionnal Information

Nepicastat (SYN-117) HCl is a potent and selective inhibitor of both bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors. Phase 2.

Storage Conditions

2 years -80 in solvent

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