R547
Product Specifications
CAS Number
741713-40-6
Synonyms
Ro 4584820
Target
CDK
Applications
Cell Cycle
Smiles
COC1=C (C (=C (C=C1) F) F) C (=O) C2=CN=C (N=C2N) NC3CCN (CC3) S (=O) (=O) C
Molecular Formula
C18H21F2N5O4S
Additionnal Information
R547 (Ro 4584820) is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM. It is less potent to CDK7 and GSK3α/β, while inactive to other kinases. Phase 1.
Storage Conditions
2 years -80 in solvent
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