ICG-001
Product Specifications
CAS Number
780757-88-2 (relative stereochemistry) ; 847591-62-2 (absolute stereochemistry)
Target
Wnt/beta-catenin
Applications
Cytoskeletal Signaling
Smiles
C1CN (C2CN (C (=O) C (N2C1=O) CC3=CC=C (C=C3) O) CC4=CC=CC5=CC=CC=C54) C (=O) NCC6=CC=CC=C6
Molecular Formula
C33H32N4O4
Additionnal Information
ICG-001 antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to CREB-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coactivator p300. ICG-001 induces apoptosis.
Storage Conditions
2 years -80 in solvent
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