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SIB 1757

Product Specifications

CAS Number

31993-01-8

Target

GluR

Applications

Neuronal Signaling

Smiles

CC1=NC (=C (C=C1) O) N=NC2=CC=CC=C2

Molecular Formula

C12H11N3O

Additionnal Information

SIB 1757 is a highly selective, noncompetitive antagonist of metabotropic glutamate receptor type 5 (mGluR5) with IC50 of 0.4 μM at hmGluR5 compared with >30 μM at hmGluR1b, hmGluR2, hmGluR4, hmGluR6, hmGluR7 and hmGluR8.

Storage Conditions

3 years -20°C powder

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